Journal article

Incidence, Progression, and Patterns of Multimorbidity in Community-Dwelling Middle-Aged Men and Women

Xianwen Shang, Wei Peng, Edward Hill, Cassandra Szoeke, Mingguang He, Lei Zhang

Frontiers in Public Health | FRONTIERS MEDIA SA | Published : 2020

Abstract

Background: Determining the incidence, progression, and patterns of multimorbidity are important for the prevention, management, and treatment of concurrence of multiple conditions. This study aimed to analyze major multimorbidity patterns and the association of the onset of a primary condition or combinations of a primary and a secondary condition with the progression to subsequent conditions. Methods: We included 53,867 participants aged 45-64 years from the 45 and Up Study who were free of 10 predefined chronic conditions at baseline (2006-2009). The incidence of multimorbidity (coexistence of ≥2, ≥3, and ≥4 conditions) was identified using the claims database until December 31, 2016. The..

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Grants

Awarded by Fundamental Research Funds of the State Key Laboratory in Ophthalmology, National Natural Science Foundation of China


Awarded by National Natural Science Foundation of China


Awarded by Outstanding Young Scholars Funding


Awarded by Xi'an Jiaotong University Basic Research and Profession Grant


Awarded by Xi'an Jiaotong University Young Talent Support Grant


Funding Acknowledgements

MH receives support from the University of Melbourne at Research Accelerator Program and the Center for Eye Research Australia Foundation. The Center for Eye Research Australia receives Operational Infrastructure Support from the Victorian State Government. The specific project was funded by the Australia China Research Accelerator Program at Center for Eye Research Australia. Professor Mingguang He is also supported by the Fundamental Research Funds of the State Key Laboratory in Ophthalmology, National Natural Science Foundation of China (81420108008). The sponsor or funding organization had no role in the design or conduct of this research. LZ was supported by the National Natural Science Foundation of China (Grant number: 8191101420); Outstanding Young Scholars Funding (Grant number: 3111500001); Xi'an Jiaotong University Basic Research and Profession Grant (Grant number: xtr022019003) and Xi'an Jiaotong University Young Talent Support Grant (Grant number: YX6J004). CS was supported by the National Health and Medical Research Council.