Cost-effectiveness of a lifestyle intervention in high-risk individuals for diabetes in a low- and middle-income setting: Trial-based analysis of the Kerala Diabetes Prevention Program

Thirunavukkarasu Sathish; Brian Oldenburg; Kavumpurathu R Thankappan; Pilvikki Absetz; Jonathan E Shaw; Robyn J Tapp; Paul Z Zimmet; Sajitha Balachandran; Suman S Shetty; Zahra Aziz; Ajay Mahal

Journal article

Cost-effectiveness of a lifestyle intervention in high-risk individuals for diabetes in a low- and middle-income setting: Trial-based analysis of the Kerala Diabetes Prevention Program

Thirunavukkarasu Sathish, Brian Oldenburg, Kavumpurathu R Thankappan, Pilvikki Absetz, Jonathan E Shaw, Robyn J Tapp, Paul Z Zimmet, Sajitha Balachandran, Suman S Shetty, Zahra Aziz, Ajay Mahal

BMC MEDICINE | BMC | Published : 2020

DOI: 10.1186/s12916-020-01704-9

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Abstract

BACKGROUND: Data on the cost-effectiveness of lifestyle-based diabetes prevention programs are mostly from high-income countries, which cannot be extrapolated to low- and middle-income countries. We performed a trial-based cost-effectiveness analysis of a lifestyle intervention targeted at preventing diabetes in India. METHODS: The Kerala Diabetes Prevention Program was a cluster-randomized controlled trial of 1007 individuals conducted in 60 polling areas (electoral divisions) in Kerala state. Participants (30-60 years) were those with a high diabetes risk score and without diabetes on an oral glucose tolerance test. The intervention group received a 12-month peer-support lifestyle interven..

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University of Melbourne Researchers

Sathish Thirunavukkarasu Author Melbourne School of Population and Global Health

Ajay Mahal Author Melbourne School of Population and Global Health

Robyn Tapp Author Melbourne School of Population and Global Health

Related Projects (1)

KERALA DIABETES PREVENTION PROGRAM (K-DPP): A CLUSTER RCT OF ITS EFFECTIVENESS AND COST-EFFECTIVENESS

The prevalence of type 2 diabetes mellitus (T2DM) in developing countries has increased dramatically. Action is now urgently required to dev..

Grants

Awarded by National Health and Medical Research Council, Australia

Awarded by ASCEND Program - Fogarty International Centre of the National Institutes of Health (NIH)

Funding Acknowledgements

K-DPP was funded by the National Health and Medical Research Council, Australia (Project Grant ID 1005324). TS was supported by the Victoria India Doctoral Scholarship (VIDS) for his PhD at the University of Melbourne, Australia. TS was also supported by the ASCEND Program, funded by the Fogarty International Centre of the National Institutes of Health (NIH) under Award Number: D43TW008332. We also acknowledge Peers for Progress, a program of the American Academy of Family Physicians Foundation supported by the Eli Lily and Company Foundation. The contents of this paper are solely the responsibility of the authors and do not reflect the views of NHMRC, NIH, Peers for Progress, or the ASCEND Program.