Journal article

Laminin coated diamond electrodes for neural stimulation

Md Kabir Uddin Sikder, Wei Tong, Hitesh Pingle, Peter Kingshott, Karina Needham, Mohit N Shivdasani, James B Fallon, Peter Seligman, Michael R Ibbotson, Steven Prawer, David J Garrett

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS | ELSEVIER | Published : 2021

Abstract

The performance of many implantable neural stimulation devices is degraded due to the loss of neurons around the electrodes by the body's natural biological responses to a foreign material. Coating of electrodes with biomolecules such as extracellular matrix proteins is one potential route to suppress the adverse responses that lead to loss of implant functionality. Concurrently, however, the electrochemical performance of the stimulating electrode must remain optimal to continue to safely provide sufficient charge for neural stimulation. We have previously found that oxygen plasma treated nitrogen included ultrananocrystalline diamond coated platinum electrodes exhibit superior charge injec..

View full abstract

Grants

Awarded by National Health and Medical Research Council (NHMRC) of Australia


Awarded by Australian Research Council (ARC)


Funding Acknowledgements

WT is supported by a Medical/Science Grant from the CASS Foundation. DJG is supported by the National Health and Medical Research Council (NHMRC) of Australia, grant GNT1101717. The Australian Research Council (ARC) is acknowledged for funding a Ph.D. scholarship for HP through a Discovery Project (DP120103405).