Journal article

Changing consumption of resources for respiratory support and short-term outcomes in four consecutive geographical cohorts of infants born extremely preterm over 25 years since the early 1990s

Jeanie LY Cheong, Joy E Olsen, Li Huang, Kim M Dalziel, Rosemarie A Boland, Alice C Burnett, Anjali Haikerwal, Alicia J Spittle, Gillian Opie, Alice E Stewart, Leah M Hickey, Peter J Anderson, Lex W Doyle

BMJ OPEN | BMJ PUBLISHING GROUP | Published : 2020

Abstract

OBJECTIVES: It is unclear how newer methods of respiratory support for infants born extremely preterm (EP; 22-27 weeks gestation) have affected in-hospital sequelae. We aimed to determine changes in respiratory support, survival and morbidity in EP infants since the early 1990s. DESIGN: Prospective longitudinal cohort study. SETTING: The State of Victoria, Australia. PARTICIPANTS: All EP births offered intensive care in four discrete eras (1991-1992 (24 months): n=332, 1997 (12 months): n=190, 2005 (12 months): n=229, and April 2016-March 2017 (12 months): n=250). OUTCOME MEASURES: Consumption of respiratory support, survival and morbidity to discharge home. Cost-effectiveness ratios describ..

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Grants

Awarded by National Health and Medical Research Council of Australia (Centre of Clinical Research Excellence)


Awarded by National Health and Medical Research Council of Australia (Centre of Research Excellence)


Awarded by National Health and Medical Research Council of Australia


Awarded by Medical Research Future Fund of Australia


Funding Acknowledgements

The National Health and Medical Research Council of Australia (Centre of Clinical Research Excellence #546519; Centre of Research Excellence #1060733 & #1153176; Project Grant #108702; Career Development Fellowship #1108714 to AJS; Senior Research Fellowship #1081288 to PJA), the Medical Research Future Fund of Australia (Career Development Fellowship #1141354 to JLYC) and the Victorian Government's Operational Infrastructure Support Programme.