Journal article

International consensus recommendations on the diagnostic work-up for malformations of cortical development

Renske Oegema, Tahsin Stefan Barakat, Martina Wilke, Katrien Stouffs, Dina Amrom, Eleonora Aronica, Nadia Bahi-Buisson, Valerio Conti, Andrew E Fry, Tobias Geis, David Gomez Andres, Elena Parrini, Ivana Pogledic, Edith Said, Doriette Soler, Luis M Valor, Maha S Zaki, Ghayda Mirzaa, William B Dobyns, Orly Reiner Show all

Nature Reviews Neurology | NATURE PUBLISHING GROUP | Published : 2020


Malformations of cortical development (MCDs) are neurodevelopmental disorders that result from abnormal development of the cerebral cortex in utero. MCDs place a substantial burden on affected individuals, their families and societies worldwide, as these individuals can experience lifelong drug-resistant epilepsy, cerebral palsy, feeding difficulties, intellectual disability and other neurological and behavioural anomalies. The diagnostic pathway for MCDs is complex owing to wide variations in presentation and aetiology, thereby hampering timely and adequate management. In this article, the international MCD network Neuro-MIG provides consensus recommendations to aid both expert and non-expe..

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Awarded by COST Action

Funding Acknowledgements

This article represents a consensus document based on three Neuro-MIG network meetings, which were supported by COST Action CA16118. The authors would like to thank all members of the network for their participation and feedback.