Second International Guidelines for the Diagnosis and Management of Hereditary Hemorrhagic Telangiectasia
Marie E Faughnan, Johannes J Mager, Steven W Hetts, Valerie A Palda, Kelly Lang-Robertson, Elisabetta Buscarini, Erik Deslandres, Raj S Kasthuri, Andrea Lausman, David Poetker, Felix Ratjen, Mark S Chesnutt, Marianne Clancy, Kevin J Whitehead, Hanny Al-Samkari, Murali Chakinala, Miles Conrad, Daniel Cortes, Claudia Crocione, Jama Darling Show all
Annals of Internal Medicine | AMER COLL PHYSICIANS | Published : 2020
Description: Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disease with an estimated prevalence of 1 in 5000 that is characterized by the presence of vascular malformations (VMs). These result in chronic bleeding, acute hemorrhage, and complications from shunting through VMs. The goal of the Second International HHT Guidelines process was to develop evidence-based consensus guidelines for the management and prevention of HHT-related symptoms and complications. Methods: The guidelines were developed using the AGREE II (Appraisal of Guidelines for Research and Evaluation II) framework and GRADE (Grading of Recommendations Assessment, Development and Evaluation) methodol..View full abstract
By the Christopher McMahon Family and Cure HHT. Dr. Faughnan is supported by the Nelson Arthur Hyland Foundation and the Li Ka Shing Knowledge Institute of St Michael's Hospital.