Frailty and outcomes from pneumonia in critical illness: a population-based cohort study
Jai N Darvall, Rinaldo Bellomo, Michael Bailey, Eldho Paul, Paul J Young, Kenneth Rockwood, David Pilcher
British Journal of Anaesthesia | ELSEVIER SCI LTD | Published : 2020
Background A threshold Clinical Frailty Scale (CFS) of 5 (indicating mild frailty) has been proposed to guide ICU admission for UK patients with coronavirus disease 2019 (COVID-19) pneumonia. However, the impact of frailty on mortality with (non-COVID-19) pneumonia in critical illness is unknown. We examined the triage utility of the CFS in patients with pneumonia requiring ICU. Methods We conducted a retrospective cohort study of adult patients admitted with pneumonia to 170 ICUs in Australia and New Zealand from January 1, 2018 to September 31, 2019. We classified patients as: non-frail (CFS 1–4) frail (CFS 5–8), mild/moderately frail (CFS 5–6),and severe/very severely frail (CFS 7–8). We ..View full abstract
This research was conducted during the tenure of a Health Research Council of New Zealand Clinical Practitioner Fellowship held by PJY. The Medical Research Institute of New Zealand is supported by Independent Research Organisation funding from the Health Research Council of New Zealand.