In Vitro α-Glucosidase and α-Amylase Inhibitory Activities of Free and Bound Phenolic Extracts from the Bran and Kernel Fractions of Five Sorghum Grain Genotypes
Yun Xiong, Ken Ng, Pangzhen Zhang, Robyn Dorothy Warner, Shuibao Shen, Hsi-Yang Tang, Zijian Liang, Zhongxiang Fang
Foods | MDPI AG | Published : 2020
Diabetes is a global health challenge. Currently, an effective treatment for diabetes is to reduce the postprandial hyperglycaemia by inhibiting the carbohydrate hydrolysing enzymes in the digestive system. In this study, we investigated the in vitro α-glucosidase and α-amylase inhibitory effects of free and bound phenolic extracts, from the bran and kernel fractions of five sorghum grain genotypes. The results showed that the inhibitory effect of sorghum phenolic extracts depended on the phenolic concentration and composition. Sorghum with higher phenolic contents generally had higher inhibitory activity. Among the tested extracts, the brown sorghum (IS131C)-bran-free extract (BR-bran-free,..View full abstract
Awarded by Taiyuan Brand Will Firm Biotechnology Development Co., Ltd., Taiyuan, Shanxi, China
This work was financially supported by Taiyuan Brand Will Firm Biotechnology Development Co., Ltd., Taiyuan, Shanxi, China (project No. GL 022055-TA 39201) and a Melbourne Research Scholarship from the University of Melbourne, Parkville, Victoria, Australia.