Journal article
Feelings of depression, pain and walking difficulties have the largest impact on the quality of life of people with multiple sclerosis, irrespective of clinical phenotype
Y Zhang, BV Taylor, S Simpson, L Blizzard, JA Campbell, AJ Palmer, I van der Mei
Multiple Sclerosis Journal | SAGE PUBLICATIONS LTD | Published : 2021
Abstract
Background: The symptoms that have the largest impact on health-related quality of life (HRQoL) in people with multiple sclerosis (MS) may vary by MS phenotype (relapsing-remitting MS (RRMS), secondary progressive MS (SPMS) and primary progressive MS (PPMS)). Knowing these symptoms assists in symptom management. Objective: To examine the associations between 13 common MS symptoms and HRQoL in the total sample and stratified by MS phenotype. Method: The study included 1985 participants. HRQoL was measured with two multi-attribute utility instruments: assessment of quality of life with eight dimensions (AQoL-8D) and European quality of life with five dimensions and five levels for each dimensi..
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Funding Acknowledgements
The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This study was funded by MS Research Australia. We sincerely thank all participants of the Australian MS Longitudinal Study for their support and willingness to complete surveys.