Interrupting Prolonged Sitting and Endothelial Function in Polycystic Ovary Syndrome
Frances C Taylor, David W Dunstan, Elly Fletcher, Melanie K Townsend, Robyn N Larsen, Kym Rickards, Nirav Maniar, Matthew Buman, Paddy C Dempsey, Anju E Joham, Neale Cohen, Neville Owen, Lisa J Moran, Daniel J Green
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE | LIPPINCOTT WILLIAMS & WILKINS | Published : 2021
PURPOSE: In healthy adults, the impairment of vascular function associated with prolonged sitting can be mitigated with intermittent brief bouts of activity. It is unknown whether these benefits extend to women with polycystic ovary syndrome (PCOS), in whom vascular function is typically impaired and sitting time is high. We examined the acute effect of regularly interrupting sitting time with brief simple resistance activities (SRA) on vascular function in PCOS. METHODS: In a randomized crossover trial, 13 physically inactive women with PCOS (18-45 yr) completed two 3.5-h conditions: 1) uninterrupted sitting (SIT) and 2) sitting interrupted by 3-min bouts of SRA every 30 min. Femoral artery..View full abstract
Awarded by NHMRC Centre of Research Excellence
Awarded by NHMRC Fellowships scheme
This research was supported by the NHMRC Centre of Research Excellence (grant no. 1057608) and the Victorian Government OIS scheme. D. W. D., D. J. G., P. C. D., and N. O. are supported by the NHMRC Fellowships scheme (grant no. 1142685). L. J. M. is supported by a National Heart Foundation Future Leader Fellowship.