Journal article

Interrupting Prolonged Sitting and Endothelial Function in Polycystic Ovary Syndrome

Frances C Taylor, David W Dunstan, Elly Fletcher, Melanie K Townsend, Robyn N Larsen, Kym Rickards, Nirav Maniar, Matthew Buman, Paddy C Dempsey, Anju E Joham, Neale Cohen, Neville Owen, Lisa J Moran, Daniel J Green

MEDICINE AND SCIENCE IN SPORTS AND EXERCISE | LIPPINCOTT WILLIAMS & WILKINS | Published : 2021

Abstract

PURPOSE: In healthy adults, the impairment of vascular function associated with prolonged sitting can be mitigated with intermittent brief bouts of activity. It is unknown whether these benefits extend to women with polycystic ovary syndrome (PCOS), in whom vascular function is typically impaired and sitting time is high. We examined the acute effect of regularly interrupting sitting time with brief simple resistance activities (SRA) on vascular function in PCOS. METHODS: In a randomized crossover trial, 13 physically inactive women with PCOS (18-45 yr) completed two 3.5-h conditions: 1) uninterrupted sitting (SIT) and 2) sitting interrupted by 3-min bouts of SRA every 30 min. Femoral artery..

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University of Melbourne Researchers

Grants

Awarded by NHMRC Centre of Research Excellence


Awarded by NHMRC Fellowships scheme


Funding Acknowledgements

This research was supported by the NHMRC Centre of Research Excellence (grant no. 1057608) and the Victorian Government OIS scheme. D. W. D., D. J. G., P. C. D., and N. O. are supported by the NHMRC Fellowships scheme (grant no. 1142685). L. J. M. is supported by a National Heart Foundation Future Leader Fellowship.