Journal article

Bone health in young adult survivors born extremely preterm or extremely low birthweight in the post surfactant era

Anjali Haikerwal, Lex W Doyle, George Patton, Suzanne M Garland, Michael M Cheung, John D Wark, Jeanie LY Cheong

Bone | ELSEVIER SCIENCE INC | Published : 2021


BACKGROUND: Most infants born extremely preterm (EP; <28 weeks' gestation) or extremely low birthweight (ELBW; 2499 g birthweight), and within the EP/ELBW group examine perinatal and later variables associated with long term bone health. METHODS: A geographic cohort comprising all 297 survivors born EP/ELBW in 1991-92 in the state of Victoria, Australia, and 260 contemporaneous controls (>2499 g birthweight) were recruited into a longitudinal study from birth. At age 25 years, investigations included dual energy X ray absorptiometry and peripheral quantitative computed tomography to measure bone, muscle and soft tissue variables, and fasting blood samples to measure serum 25 hydroxyvitamin D..

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Awarded by National Health and Medical Research Council of Australia (Centre of Research Excellence)

Funding Acknowledgements

Supported by grants from the National Health and Medical Research Council of Australia (Centre of Research Excellence #1060733; #1153176; Project Grant #1104300; Career Development Fellowship #1141354 to JLYC), and Operational Infrastructure Support Program from the state government of Victoria, Australia. The content is solely the responsibility of the authors and does not necessarily represent the official views of the funding agencies. The funding sources had no role in the design and conduct of the study; collection, management, analysis, and interpretation of data; preparation, review, or approval of the manuscript; or decision to submit the manuscript for publication.