Dynamic Neural Interactions Supporting the Cognitive Reappraisal of Emotion

Trevor Steward; Christopher G Davey; Alec J Jamieson; Katerina Stephanou; Carles Soriano-Mas; Kim L Felmingham; Ben J Harrison

Journal article

Dynamic Neural Interactions Supporting the Cognitive Reappraisal of Emotion

Trevor Steward, Christopher G Davey, Alec J Jamieson, Katerina Stephanou, Carles Soriano-Mas, Kim L Felmingham, Ben J Harrison

CEREBRAL CORTEX | OXFORD UNIV PRESS INC | Published : 2021

DOI: 10.1093/cercor/bhaa268

Abstract

The cognitive reappraisal of emotion is hypothesized to involve frontal regions modulating the activity of subcortical regions such as the amygdala. However, the pathways by which structurally disparate frontal regions interact with the amygdala remains unclear. In this study, 104 healthy young people completed a cognitive reappraisal task. Dynamic causal modeling (DCM) was used to map functional interactions within a frontoamygdalar network engaged during emotion regulation. Five regions were identified to form the network: the amygdala, the presupplementary motor area (preSMA), the ventrolateral prefrontal cortex (vlPFC), dorsolateral prefrontal cortex (dlPFC), and ventromedial prefrontal ..

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University of Melbourne Researchers

Chris Davey Author Psychiatry

Kim Felmingham Author Melbourne School of Psychological Sciences

Ben Harrison Author Psychiatry

Trevor Steward Author Melbourne School of Psychological Sciences

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Grants

Awarded by National Health and Medical Research Council of Australia (NHMRC)

Awarded by NHMRC Career Development Fellowship

Awarded by NHMRC/Medical Research Future Fund (MRFF) Investigator Grant

Funding Acknowledgements

This work was supported by a National Health and Medical Research Council of Australia (NHMRC) Project Grant (1064643) to B.J.H. A.J.J. was supported by an Australian Government Research Training Program Scholarship. B.J.H. was supported by an NHMRC Career Development Fellowship (1124472). C.G.D. was supported by an NHMRC Career Development Fellowship (1141738). T.S. was supported by the University of Melbourne McKenzie Fellowship and an NHMRC/Medical Research Future Fund (MRFF) Investigator Grant (MRF1193736).