Journal article

Multimorbidity, glycaemic variability and time in target range in people with type 2 diabetes: A baseline analysis of the GP-OSMOTIC trial

Jason I Chiang, Jo-Anne Manski-Nankervis, Sharmala Thuraisingam, Alicia Jenkins, David O'Neal, Frances S Mair, Bhautesh Dinesh Jani, Barbara I Nicholl, John Furler

Diabetes Research and Clinical Practice | ELSEVIER IRELAND LTD | Published : 2020

Abstract

AIMS: To explore associations between multimorbidity condition counts (total; concordant (diabetes-related); discordant (unrelated to diabetes)) and glycaemia (HbA1c; glycaemic variability (GV); time in range (TIR)) using data from a randomised controlled trial examining effectiveness of continuous glucose monitoring (CGM) in people with type 2 diabetes (T2D). METHODS: Cross-sectional study: 279 people with T2D using baseline data from the General Practice Optimising Structured MOnitoring To Improve Clinical outcomes (GP-OSMOTIC) trial from 25 general practices in Australia. Number of long-term conditions (LTCs) in addition to T2D used to quantify total/concordant/discordant multimorbidity c..

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Grants

Awarded by National Health and Medical Research Council (NHMRC) of Australia


Awarded by NHMRC


Funding Acknowledgements

The GP-OSMOTIC trial was supported by a Project Grant from the National Health and Medical Research Council (NHMRC) of Australia (ID APP1104241). Additional funding was provided by Sanofi Australia. In-kind support (Flash Libre Pro reader devices, sensors, and software) was provided by Abbott Diabetes Care. JC was supported by a NHMRC postgraduate scholarship (ID APP1168372). AJ was supported by a NHMRC Practitioner Fellowship and was a Sydney Medical School Foundation Fellow. JMN was supported by a Next Generation Clinical Researchers Program TRIP Fellowship Funded from the Medical Research Future Fund.