Octreotide for resuscitation of cardiac arrest due to carcinoid crisis precipitated by novel peptide receptor radionuclide therapy (PRRT): A case report
Jayesh Dhanani, David A Pattison, Matthew Burge, Julian Williams, Bernhard Riedel, Rodney J Hicks, Michael C Reade
Journal of Critical Care | W B SAUNDERS CO-ELSEVIER INC | Published : 2020
Peptide receptor radionuclide therapy (PRRT) is an effective treatment for metastatic carcinoid tumours but can precipitate a carcinoid crisis through release of stored bioamines. Cardiac arrest is an uncommon manifestation of carcinoid crisis and has never been reported as a complication of PRRT. We report a case of a 58-year old female who suffered from cardiac arrest following PRRT for metastatic carcinoid tumour. She was successfully resuscitated using intravenous octreotide following 22 min of failure to resuscitate with a standard advanced cardiac life support protocol. Following resuscitation, severe carcinoid heart disease was diagnosed, and the patient subsequently underwent success..View full abstract
Dr. Jayesh Dhanani would like to acknowledge the Metro North Clinician Researcher Fellowship 2020.