Sex-based differences in the outcomes of total hip and knee arthroplasty: a narrative review
Annabelle LC Choong, Cade Shadbolt, Michelle M Dowsey, Peter FM Choong
ANZ Journal of Surgery | WILEY | Published : 2020
Total joint arthroplasty (TJA) is an effective treatment for end-stage osteoarthritis, which aims to alleviate pain and improve function and mobility. Despite the remarkable success of TJA, complications can arise, leading to unplanned hospital readmission, implant failure, morbidity and mortality. Recently, there has been a growing interest in analysing sex-based differences in diseases and response to medical interventions. This review summaries evidence pertaining to the widening gap between men and women regarding the utilization and outcome of TJA surgery. Interactions between sex and patient-reported outcome, implant failure and medical complication are complex and often demonstrate co..View full abstract
Awarded by NHMRC Career Development Fellowship
Awarded by NHMRC Practitioner Fellowship
MD holds a NHMRC Career Development Fellowship (1122526) and University of Melbourne Dame Kate Campbell Fellowship. PC holds a NHMRC Practitioner Fellowship (1154203). CS acknowledges being supported by an Australian Government Research Training Program Scholarship.