Health Service Use and Quality of Life Recovery 12 Months Following Major Osteoporotic Fracture: Latent Class Analyses of the International Costs and Utilities Related to Osteoporotic Fractures Study (ICUROS)

Jason Talevski; Kerrie M Sanders; Ljoudmila Busija; Alison Beauchamp; Gustavo Duque; Fredrik Borgstrom; John A Kanis; Axel Svedbom; Catherine Connaughton; Amanda L Stuart; Sharon L Brennan-Olsen

Journal article

Health Service Use and Quality of Life Recovery 12 Months Following Major Osteoporotic Fracture: Latent Class Analyses of the International Costs and Utilities Related to Osteoporotic Fractures Study (ICUROS)

Jason Talevski, Kerrie M Sanders, Ljoudmila Busija, Alison Beauchamp, Gustavo Duque, Fredrik Borgstrom, John A Kanis, Axel Svedbom, Catherine Connaughton, Amanda L Stuart, Sharon L Brennan-Olsen

Journal of Bone and Mineral Research | WILEY | Published : 2020

DOI: 10.1002/jbmr.4181

Abstract

Major osteoporotic fractures (MOFs) are associated with a rapid decline in health-related quality of life (HRQoL); however, there is limited knowledge about which healthcare services positively affect HRQoL postfracture. This study aimed to identify specific combinations of health service use associated with recovery of HRQoL 12 months post-MOF. The analyses included 4126 adults aged ≥50 years with an MOF (1657 hip, 1354 distal forearm, 681 vertebrae, 434 humerus) participating in the International Costs and Utilities Related to Osteoporotic fractures Study (ICUROS), a multinational observational study (Australia, Austria, Estonia, France, Italy, Lithuania, Mexico, Russia, Spain, United King..

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University of Melbourne Researchers

Kerrie Sanders Author

Catherine Connaughton Author Medicine, Dentistry and Health Sciences

Alison Beauchamp Author

Gustavo Duque Author

Sharon Brennan-Olsen Author

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Grants

Awarded by Australian National Health and Medical Research Council (NHMRC) Postgraduate Scholarship

Awarded by NHMRC Career Development Fellowship

Awarded by NHMRC

Awarded by National Council of Science and Technology (CONACyT)

Awarded by Estonian Science Foundation

Funding Acknowledgements

JT is supported by an Australian National Health and Medical Research Council (NHMRC) Postgraduate Scholarship (1151089) and SLB-O is supported by a NHMRC Career Development Fellowship (1107510). We are grateful to the Quality of Life and Epidemiology Working Group of the Committee of Scientific Advisors for the International Osteoporosis Foundation (IOF) under whose supervision this study was undertaken. At the international level, the ICUROS was sponsored by Amgen, Eli Lilly, Medtronic (Kyphon), Novartis, Sanofi-Aventis Wyeth and Servier. We acknowledge the Quality of Life and Epidemiology Working Group: Jonathan Adachi, Frederik Borgstrom, Patricia Clark, Cyrus Cooper (co-chair), Manuel Diaz Curiel, Hans Peter Dimai, Mickael Hiligsmann, John Kanis (co-chair), Edith Lau, Paul Lips, Mickael Lewiecki, Roman Lorenc, Eugene McCloskey, Sergio Ortolani, Alexandra Papaioannou, Stuart Silverman, and Pawel Szulc. In Australia, the study was supported by the NHMRC (628422) with subsidiary funding support from Merck Australia Pty Ltd. In Austria, the study was sponsored by Central Association of Austrian Social Security Institution, the Austrian Society for Bone and Mineral Research (AuSBMR), Merck Sharp & Dohme, Nycomed, Roche and Daiichi-Sankyo GmbH. In Mexico, the study was supported by the National Council of Science and Technology (CONACyT) grant El 2008-01-87106. In Lithuania, the study was supported by the National Osteoporosis Center. In Estonia, the study was supported by Estonian Science Foundation (Grant 9368).