Patient-Reported Outcomes Following Total Knee Replacement in Patients < 65 Years of Age-A Systematic Review and Meta-Analysis

Jason Trieu; Daniel J Gould; Chris Schilling; Tim Spelman; Michelle M Dowsey; Peter F Choong

Journal article

Patient-Reported Outcomes Following Total Knee Replacement in Patients < 65 Years of Age-A Systematic Review and Meta-Analysis

Jason Trieu, Daniel J Gould, Chris Schilling, Tim Spelman, Michelle M Dowsey, Peter F Choong

JOURNAL OF CLINICAL MEDICINE | MDPI | Published : 2020

DOI: 10.3390/jcm9103150

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Abstract

An increasing number of total knee replacements (TKRs) are being performed in response to the growing burden of osteoarthritis. Patients <65 years of age represent the fastest growing group of TKR recipients and are expected to account for an increasing number of primary and revision procedures. Concerns have been raised about the outcomes that can be expected by this age demographic who are more active, physically demanding, and have longer life expectancies compared to older TKR recipients. This systematic review and meta-analysis evaluated the effectiveness of TKR for osteoarthritis in patients <65 years of age, compared to older individuals. A systematic search of Embase and Medline was ..

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University of Melbourne Researchers

Daniel Gould Author

Chris Schilling Author

Timothy Spelman Author

Michelle Dowsey Author

Related Projects (2)

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Grants

Awarded by University of Melbourne, Parkville, Victoria, Australia through the National Health and Medical Research Council's Centre of Research Excellence in Total Joint Replacement at the Department of Surgery, St Vincent's Hospital, Fitzroy, Victoria, Australia

Awarded by NHMRC Career Development Fellowship

Awarded by NHMRC Early Career Fellowship

Awarded by NHMRC Practitioner Fellowship

Funding Acknowledgements

This research received no external funding. JT is supported by a Research Training Program Scholarship from the University of Melbourne, Parkville, Victoria, Australia provided through the National Health and Medical Research Council's Centre of Research Excellence in Total Joint Replacement (APP1116325) at the Department of Surgery, St Vincent's Hospital, Fitzroy, Victoria, Australia. MD is the recipient of an NHMRC Career Development Fellowship (APP1122526) and University of Melbourne Dame Kate Campbell Fellowship. TS is the recipient of an NHMRC Early Career Fellowship (APP1130685). PC is the recipient of an NHMRC Practitioner Fellowship (APP1154203).