Journal article

Development and validation of a screening questionnaire for psychogenic nonepileptic seizures

David Trainor, Emma Foster, Maria Rychkova, Michael Lloyd, Michelle Leong, Albert D Wang, Dennis Velakoulis, Terence J O'Brien, Patrick Kwan, Samantha M Loi, Charles B Malpas

Epilepsy & Behavior | ACADEMIC PRESS INC ELSEVIER SCIENCE | Published : 2020


OBJECTIVE: Epilepsy and psychogenic nonepileptic seizures (PNES) are serious conditions, associated with substantial morbidity and mortality. Although prompt diagnosis is essential, these conditions are frequently misdiagnosed, delaying appropriate treatment. We developed and validated the Anxiety, Abuse, and Somatization Questionnaire (AASQ), a quick and clinically practical tool to differentiate PNES from epilepsy. METHOD: We retrospectively identified psychological variables that differentiated epilepsy from PNES in a discovery cohort of patients admitted to a video-electroencephalography monitoring (VEM) unit from 2002 to 2017. From these findings, we developed the AASQ and prospectively..

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Funding Acknowledgements

Dr. Foster is supported by the National Health and Medical Research Council (NHMRC) of Australia, The Royal Australasian College of Physicians Research Entry Scholarship, and AVANT Doctors in Training Scholarship. Dr. Loi is also supported by the NHMRC. This funding is unrelated to the current study.