Journal article

A multicentre, randomised trial of stabilisation with nasal high flow during neonatal endotracheal intubation (the SHINE trial): a study protocol

Kate A Hodgson, Louise S Owen, Camille Omar Kamlin, Calum T Roberts, Susan M Donath, Peter G Davis, Brett James Manley

BMJ Open | BMJ PUBLISHING GROUP | Published : 2020


INTRODUCTION: Neonatal endotracheal intubation is an essential but potentially destabilising procedure. With an increased focus on avoiding mechanical ventilation, particularly in preterm infants, there are fewer opportunities for clinicians to gain proficiency in this important emergency skill. Rates of successful intubation at the first attempt are relatively low, and adverse event rates are high, when compared with intubations in paediatric and adult populations. Interventions to improve operator success and patient stability during neonatal endotracheal intubations are needed. Using nasal high flow therapy extends the safe apnoea time of adults undergoing upper airway surgery and during ..

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Awarded by National Health and Medical Research Council

Funding Acknowledgements

This work was supported by National Health and Medical Research Council program grant #1113902. Nasal high flow equipment and consumables have been supplied by Vapotherm.