Journal article
Needles in a haystack: Extremely rare invasive fungal infections reported in FungiScopeⓇ—Global Registry for Emerging Fungal Infections
J Salmanton-García, P Koehler, A Kindo, I Falces-Romero, J García-Rodríguez, Z Ráčil, SCA Chen, N Klimko, G Desoubeaux, GR Thompson, MÁ Benítez-Peñuela, JY Rodríguez, DC Sheppard, M Hoenigl, Y Le Govic, H Badali, JW Baddley, J Chander, PR Ingram, DL Pakstis Show all
Journal of Infection | W B SAUNDERS CO LTD | Published : 2020
Abstract
Objectives: Emerging invasive fungal infections (IFI) have become a notable challenge. Apart from the more frequently described fusariosis, lomentosporiosis, mucormycosis, scedosporiosis, and certain dematiaceae or yeasts, little is known about extremely rare IFI. Methods: Extremely rare IFI collected in the FungiScopeⓇ registry were grouped as Dematiaceae, Hypocreales, Saccharomycetales, Eurotiales, Dermatomycetes, Agaricales, and Mucorales. Results: Between 2003 and June 2019, 186 extremely rare IFI were documented in FungiScopeⓇ. Dematiaceae (35.5%), Hypocreales (23.1%), Mucorales (11.8%), and Saccharomycetales (11.3%) caused most IFI. Most patients had an underlying malignancy (38.7%) wi..
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Funding Acknowledgements
FungiScope (R) is supported by unrestricted grants of Amplyx Pharmaceuticals, Basilea Pharmaceutica, Cidara Therapeutics, F2G Ltd., Matinas BioPharma, MSD Sharp & Dohme GmbH, and SCYNEXIS Inc. FungiScope (R) has been supported in the past by unrestricted grants of Astellas Pharma, Gilead Sciences, and Pfizer Inc.