Journal article

Needles in a haystack: Extremely rare invasive fungal infections reported in FungiScope (R)-Global Registry for Emerging Fungal Infections

Jon Salmanton-Garcia, Philipp Koehler, Anupma Kindo, Iker Falces-Romero, Julio Garcia-Rodriguez, Zdenek Racil, Sharon C-A Chen, Nikolai Klimko, Guillaume Desoubeaux, George R Thompson, Miguel-Angel Benitez-Penuela, Jose-Yesid Rodriguez, Donald C Sheppard, Martin Hoenigl, Yohann Le Govic, Hamid Badali, John W Baddley, Jagdish Chander, Paul R Ingram, Diana L Pakstis Show all

JOURNAL OF INFECTION | W B SAUNDERS CO LTD | Published : 2020

Abstract

OBJECTIVES: Emerging invasive fungal infections (IFI) have become a notable challenge. Apart from the more frequently described fusariosis, lomentosporiosis, mucormycosis, scedosporiosis, and certain dematiaceae or yeasts, little is known about extremely rare IFI. METHODS: Extremely rare IFI collected in the FungiScopeⓇ registry were grouped as Dematiaceae, Hypocreales, Saccharomycetales, Eurotiales, Dermatomycetes, Agaricales, and Mucorales. RESULTS: Between 2003 and June 2019, 186 extremely rare IFI were documented in FungiScopeⓇ. Dematiaceae (35.5%), Hypocreales (23.1%), Mucorales (11.8%), and Saccharomycetales (11.3%) caused most IFI. Most patients had an underlying malignancy (38.7%) wi..

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Grants

Funding Acknowledgements

FungiScope (R) is supported by unrestricted grants of Amplyx Pharmaceuticals, Basilea Pharmaceutica, Cidara Therapeutics, F2G Ltd., Matinas BioPharma, MSD Sharp & Dohme GmbH, and SCYNEXIS Inc. FungiScope (R) has been supported in the past by unrestricted grants of Astellas Pharma, Gilead Sciences, and Pfizer Inc.