Managing HIV-associated inflammation and ageing in the era of modern ART
M Bloch, M John, D Smith, TA Rasmussen, E Wright
HIV Medicine | WILEY | Published : 2020
OBJECTIVES: This paper aims to address the concerns around ongoing immune activation, inflammation, and resistance in those ageing with HIV that represent current challenges for clinicians. METHODS: Presentations at a symposium addressing issues of ageing with HIV infection were reviewed and synthesised. RESULTS: The changing natural history and demographics of human immunodeficiency virus (HIV)-infected individuals means new challenges in contemporary management. In the early years of the epidemic,management was focussed on acute, potentially life-threatening AIDS-related complications. From initial monotherapy with first-generation antiretroviral therapy (ART), the development of combinati..View full abstract
Gilead Sciences Australia provided financial support for the research and writing of this publication via an unrestricted educational grant.