Journal article

Faecal microbiota and antimicrobial resistance gene profiles of healthy foals

Yuhong Liu, Kirsten E Bailey, Michael Dyall-Smith, Marc S Marenda, Laura Y Hardefeldt, Glenn F Browning, James R Gilkerson, Helen Billman-Jacobe

Equine Veterinary Journal | WILEY | Published : 2020


BACKGROUND: The human and domestic animal faecal microbiota can carry various antimicrobial resistance genes (ARGs), especially if they have been exposed to antimicrobials. However, little is known about the ARG profile of the faecal microbiota of healthy foals. A high-throughput qPCR array was used to detect ARGs in the faecal microbiota of healthy foals. OBJECTIVES: To characterise the faecal microbiota and ARG profiles in healthy Australian foals aged less than 1 month. STUDY DESIGN: Observational study. METHODS: The faecal microbiota and ARG profiles of 37 Thoroughbred foals with no known gastrointestinal disease or antimicrobial treatment were determined using 16S rRNA gene sequencing a..

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Funding Acknowledgements

This study was funded by the National Health and Medical Research Council through a Centres of Research Excellence grant to the National Centre for Antimicrobial Stewardship. Y. Liu received a Melbourne Research Scholarship from the University of Melbourne.