Journal article

A randomized control trial of intensive aphasia therapy after acute stroke: The Very Early Rehabilitation for SpEech (VERSE) study

Erin Godecke, Elizabeth Armstrong, Tapan Rai, Natalie Ciccone, Miranda L Rose, Sandy Middleton, Anne Whitworth, Audrey Holland, Fiona Ellery, Graeme J Hankey, Dominique A Cadilhac, Julie Bernhardt

International Journal of Stroke | SAGE PUBLICATIONS LTD | Published : 2020


BACKGROUND: Effectiveness of early intensive aphasia rehabilitation after stroke is unknown. The Very Early Rehabilitation for SpEech trial (VERSE) aimed to determine whether intensive aphasia therapy, beginning within 14 days after stroke, improved communication recovery compared to usual care. METHODS: Prospective, randomized, single-blinded trial conducted at 17 acute-care hospitals across Australia/New Zealand from 2014 to 2018. Participants with aphasia following acute stroke were randomized to receive usual care (direct usual care aphasia therapy), or one of two higher intensity regimens (20 sessions of either non-prescribed (usual care-plus or prescribed (VERSE) direct aphasia therapy..

View full abstract


Awarded by NHMRC

Awarded by National Health and Medical Research Council

Funding Acknowledgements

The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: Erin Godecke-NHMRC Funding: App1083010, APP1132468, App1153236, NIH (UK) HS&DR Program funding; Elizabeth Armstrong-NHMRC Funding: APP1132468; Tapan Rai reports no disclosures; Miranda L Rose-NHMRC Funding: App1083010, App1153236; Fiona Ellery FE reports personal fees from Florey Institute of Neurosciences and Mental Health, The University of Melbourne during the conduct of the study; Graham J Hankey has received honoraria from Bayer for lecturing at sponsored scientific symposia and consulting on advisory boards about stroke prevention in atrial fibrillation; Dominique A Cadilhac-NHMRC Funding App1063761, App1154273; Julie Bernhardt-NHMRC Funding JB-App1154904, App1058635. This study was funded by National Health and Medical Research Council (APP1044973), The Tavistock Trust for Aphasia (UK), Edith Cowan University, Australia.