Adiposity Without Obesity: Associations with Osteoporosis, Sarcopenia, and Falls in the Healthy Ageing Initiative Cohort Study
David Scott, Jonas Johansson, Peter R Ebeling, Peter Nordstrom, Anna Nordstrom
Obesity | WILEY | Published : 2020
OBJECTIVE: Obesity is commonly defined by BMI rather than adiposity, which may have differential effects on musculoskeletal health. Musculoskeletal outcomes were compared in older adults with normal adiposity and normal BMI (NA-NBMI), those with high adiposity but normal BMI (HA-NBMI), and those with high adiposity and high BMI (HA-HBMI). METHODS: In 3,411 70-year-olds, obesity was defined as BMI ≥ 30 kg/m2 and adiposity as body fat percentage ≥ 25% (men) or ≥ 35% (women) from dual-energy x-ray absorptiometry. Bone parameters were measured by dual-energy x-ray absorptiometry and peripheral quantitative computed tomography. Sarcopenia was defined as low handgrip strength with or without low a..View full abstract
Awarded by Swedish Research Council
Awarded by Australian National Health and Medical Research Council (NHMRC) RD Wright Biomedical Career Development Fellowship
Awarded by NHMRC Investigator Grant
This work was supported by the Swedish Research Council (grant number 2011-2976). DS is supported by an Australian National Health and Medical Research Council (NHMRC) RD Wright Biomedical Career Development Fellowship (GNT1123014) and an NHMRC Investigator Grant (GNT1174886).