Journal article

Long-Term Results of the RAPCO Trials

Brian F Buxton, Philip A Hayward, Jai Raman, Simon C Moten, Alexander Rosalion, Ian Gordon, Siven Seevanayagam, George Matalanis, Umberto Benedetto, Mario Gaudino, David L Hare

Circulation | LIPPINCOTT WILLIAMS & WILKINS | Published : 2020

Abstract

BACKGROUND: An internal thoracic artery graft to the left anterior descending artery is standard in coronary bypass surgery, but controversy exists on the best second conduit. The RAPCO trials (Radial Artery Patency and Clinical Outcomes) were designed to compare the long-term patency of the radial artery (RA) with that of the right internal thoracic artery (RITA) and the saphenous vein (SV). METHODS: In RAPCO-RITA (the RITA versus RA arm of the RAPCO trial), 394 patients <70 years of age (or <60 years of age if they had diabetes mellitus) were randomized to receive RA or free RITA graft on the second most important coronary target. In RAPCO-SV (the SV versus RA arm of the RAPCO trial), 225 ..

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Grants

Awarded by Heart Foundation of Australia


Funding Acknowledgements

This study was completed with assistance of grants from the Heart Foundation of Australia (G09M4392 to Drs Buxton and Hare), Johnson & Johnson (Medical) Australia, and the Sir Edward Dunlop Foundation at the Royal Australasian College of Surgeons. The funding sources had no role in the study design, data collection, analysis, interpretation, or writing of the article. Dr Benedetto is supported by the Bristol NIHR Biomedical Centre of Research. Prof Hare has been supported by a Practitioner Fellowship of the National Health and Medical Research Council of Australia.