Journal article

Matched Case-Control Study of the Long-Term Impact of Beta-Lactam Antibiotic Allergy Testing

Jason A Trubiano, Nada Marhoon, Sara Vogrin, Kyra YL Chua, Natasha E Holmes

Antimicrobial Agents and Chemotherapy | AMER SOC MICROBIOLOGY | Published : 2020

Abstract

Whereas the short-term impacts of antibiotic allergy testing on delabeling and antibiotic usage have been demonstrated, the long-term impacts have been less well defined. In a single-center matched case-control study from Melbourne, Australia, we demonstrate that a beta-lactam antibiotic allergy testing program has a significant impact on antibiotic usage and infection-related outcomes. This study supports implementation of an antibiotic allergy testing program as a standard of care of antimicrobial stewardship programs.

Grants

Awarded by National Health and Medical Research Council (NHMRC) fellowship


Funding Acknowledgements

This work was supported by the Austin Medical Research Foundation (AMRF). J.A.T. is supported by a National Health and Medical Research Council (NHMRC) fellowship (GNT 1139902) and Royal Australian College of Physicians Research Establishment Fellowship.