Journal article

Cumulative Cardiovascular Disease Risk and Triglycerides Differentially Relate to Subdomains of Executive Function in Bipolar Disorder; preliminary findings

Tamsyn E Van Rheenen, Roger S McIntyre, Vicent Balanza-Martinez, Michael Berk, Susan L Rossell



OBJECTIVES: Cardiovascular disease is disproportionally prevalent in bipolar disorder (BD) and has been linked to cognition in preliminary studies. Herein we evaluate the association between known risk factors for cardiovascular disease and executive function in BD patients compared to healthy controls. METHODS: In a sample of n=57 individuals (n=23 BD, n=34 controls) we assessed two subdomains of executive function; cognitive flexibility (using the Trail Making Test - Part B) and cognitive inhibition (using the Stroop Colour Word Interference Task). Cardiovascular risk was assessed by means of serum triglyceride levels, body mass index (BMI) and waist circumference, as well as dietary satur..

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Awarded by National Health and Medical Research Council (NHMRC)

Awarded by Instituto de Salud Carlos III

Funding Acknowledgements

The National Health and Medical Research Council (NHMRC) provided salary support to TVR (Early Career Fellowship 1088785), SR (Senior Research Fellowship 1154651) and MB (Senior Principal Research Fellowships 1059660 and 1156072). VBM acknowledges the support from Instituto de Salud Carlos III (PI16/1770, PROBILIFE study). The authors would also like to acknowledge the project specific financial support of the Helen McPherson Smith Trust and Australian Rotary Health/Bipolar Expedition. Finally, the authors would like to thank the participants in this study for their time and contribution