Journal article

Sufficient vitamin D status positively modified ventilatory function in asthmatic children following a Mediterranean diet enriched with fatty fish intervention study

Maria M Papamichael, Catherine Itsiopoulos, Katrina Lambert, Charis Katsardis, Dimitris Tsoukalas, Bircan Erbas



Asthma in children is the most prevalent allergic disease worldwide that has become a major public health priority. The objective of this study was to examine the relationship between baseline serum vitamin D status, spirometry, and fractional exhaled nitric oxide levels (FeNO) in 64 Greek children with 'mild asthma' aged 5 to 12 years (51.6% male) in a dietary intervention study. We hypothesized that baseline serum vitamin D levels modify the beneficial response of fatty fish intake on pulmonary function in asthmatic children following a Mediterranean diet. The intervention group consumed 2 fatty fish meals/week (≥150 g cooked filleted fish/meal) as part of the Mediterranean diet for six mo..

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Funding Acknowledgements

The authors are grateful to Basilopoulos and Sklavenitis supermarkets for their support to economically-disadvantaged families. The authors declare no conflicts of interest. This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. The first author is supported by an Australian Post Graduate Award PhD Scholarship administered by La Trobe University. All co-authors declare that we have seen and approved the final version of the manuscript being submitted. The authors confirm the article is the authors' original work, has not received prior publication, and is not under consideration for publication elsewhere. CK, DT, and MP were responsible for data collection. MP is the principal author of the paper. CI, BE, CK contributed in revising the first and final draft of the manuscript. BE and KL guided the statistical analysis.