Recommended Definitions of Aggressive Prostate Cancer for Etiologic Epidemiologic Research
Lauren M Hurwitz, Ilir Agalliu, Demetrius Albanes, Kathryn Hughes Barry, Sonja Berndt, Qiuyin Cai, Chu Chen, Iona Cheng, Jeanine M Genkinger, Graham G Giles, Jiaqi Huang, Corinne E Joshu, Tim J Key, Synnove Knutsen, Stella Koutros, Hilde Langseth, Sherly X Li, Robert J MacInnis, Sarah C Markt, Kathryn L Penney Show all
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE | OXFORD UNIV PRESS INC | Published : 2021
BACKGROUND: In the era of widespread prostate-specific antigen testing, it is important to focus etiologic research on the outcome of aggressive prostate cancer, but studies have defined this outcome differently. We aimed to develop an evidence-based consensus definition of aggressive prostate cancer using clinical features at diagnosis for etiologic epidemiologic research. METHODS: Among prostate cancer cases diagnosed in 2007 in the National Cancer Institute's Surveillance, Epidemiology, and End Results-18 database with follow-up through 2017, we compared the performance of categorizations of aggressive prostate cancer in discriminating fatal prostate cancer within 10 years of diagnosis, p..View full abstract
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PRECISION PUBLIC HEALTH FOR MAJOR CANCERS - NOVEL APPROACHES TO BUILDING THE GENETIC, EPIGENETIC AND LIFESTYLE KNOWLEDGE BASE FOR ASSESSING RISK AND PROGNOSIS
The Program of research seeks to increase our understanding of cancer risk. We will use our large collections of population and family-based..
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Awarded by DOD
Awarded by Cancer Research UK
Awarded by Australian National Health and Medical Research Council
This research was supported by the Intramural Research Program of the National Cancer Institute, National Institutes of Health, Department of Health and Human Services. Investigators were also supported by the following grants: U01-CA164975, U01-CA182883, U01-CA167552, P30CA006973, P30-CA006516, P30-CA008748, U01-CA063673, UM1-CA167462, U01-CA167462, K07-CA230182 (NCI/NIH/HHS), W81XWH-18-1-0330 (DOD), C8221/A19170, C8221/A29017 (Cancer Research UK), a University of Hawaii Cancer Center Seed Grant, Prostate Cancer Foundation Young Investigator Awards, and Program Grants 209057 and 1074383 and an Enabling Grant 396414 from the Australian National Health and Medical Research Council.