Journal article

Electrospun Nanodiamond-Silk Fibroin Membranes: A Multifunctional Platform for Biosensing and Wound-Healing Applications

Asma Khalid, Dongbi Bai, Amanda N Abraham, Amit Jadhav, Denver Linklater, Alex Matusica, Nguyen Duy, Billy James Murdoch, Nadia Zakhartchouk, Chaitali Dekiwadia, Philipp Reineck, David Simpson, Achini K Vidanapathirana, Shadi Houshyar, Christina A Bursill, Elena P Ivanova, Brant C Gibson

ACS Applied Materials & Interfaces | AMER CHEMICAL SOC | Published : 2020

Abstract

Next generation wound care technology capable of diagnosing wound parameters, promoting healthy cell growth, and reducing pathogenic infections noninvasively would provide patients with an improved standard of care and accelerated wound repair. Temperature is one of the indicating biomarkers specific to chronic wounds. This work reports a hybrid, multifunctional optical material platform—nanodiamond (ND)–silk membranes as biopolymer dressings capable of temperature sensing and promoting wound healing. The hybrid structure was fabricated through electrospinning, and 3D submicron fibrous membranes with high porosity were formed. Silk fibers are capable of compensating for the lack of an extrac..

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Grants

Awarded by Australian Research Council (ARC) through the Centre of Excellence for Nanoscale BioPhotonics and LIEF grant


Funding Acknowledgements

The work was also supported by the Australian Research Council (ARC) through the Centre of Excellence for Nanoscale BioPhotonics and LIEF grant (LE140100131). A.K., P.R., and S.H. acknowledge funding through the RMIT Vice-Chancellor's Research Fellowship.