Journal article

Duration of protective immunity induced by Mycoplasma gallisepticum strain ts-304 vaccine in chickens

Anna Kanci Condello, Sathya N Kulappu Arachchige, Pollob K Shil, Gregory J Underwood, Amir H Noormohammadi, Philip F Markham, Nadeeka K Wawegama, Glenn F Browning

Veterinary Microbiology | Elsevier | Published : 2020

Abstract

Mycoplasma gallisepticum (MG) is an important pathogen of poultry worldwide, causing chronic respiratory disease in chickens and turkeys. MG ts-304 is a GapA positive clone recovered from Vaxsafe MG (strain ts-11) that has been shown to be safe in chickens when delivered by the eye drop route to 3-week-old specific-pathogen-free chickens and to confer protection against challenge at 4 weeks after vaccination, as measured by tracheal mucosal thickness and air sac lesion scores. In this study, specific pathogen-free chickens (SPF) were vaccinated with a single dose of the MG ts-304 vaccine (106.0 colour changing units) at 3 weeks of age and experimentally challenged by aerosol with the virulen..

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