Journal article

Performance of 4 Creatinine-based Equations in Assessing Glomerular Filtration Rate in Adults with Diabetes

Neda Zafari, Mojtaba Lotfaliany, Graeme J O'Keefe, Kartik Kishore, Niloufar Torkamani, Richard J MacIsaac, Leonid Churilov, Elif Ekinci

The Journal of Clinical Endocrinology & Metabolism | ENDOCRINE SOC | Published : 2021


AIMS: To evaluate diagnostic performance of glomerular filtration rate (GFR) estimated by modification of diet in renal disease (MDRD), chronic kidney disease epidemiology collaboration (CKD-EPI), full age spectrum (FAS), and revised Lund-Malmö (r-LM) equations in adults with diabetes. METHODS: Individuals were included in this cross-sectional study if they had at least 1 measurement of technetium-99m diethylenetriamine-pentaacetic acid (99mTc-DTPA) GFR (mGFR) and serum creatinine (1487 patients with 2703 measures). GFR calculated by estimation equations was compared with mGFR. Diagnostic performance was assessed using concordance correlation coefficient (CCC), bias, precision, accuracy, red..

View full abstract


Funding Acknowledgements

This study was supported by the Melbourne Research Scholarship from the University of Melbourne. E.I.E. was supported by the Sir Edwards Weary Dunlop Medical Research Foundation. The study sponsor/funder was not involved in the design of the study; the collection, analysis, and interpretation of data; writing the report; and did not impose any restrictions regarding the publication of the report.