Safety, Efficacy, and Patterns of Failure After Single-Fraction Stereotactic Body Radiation Therapy (SBRT) for Oligometastases.
Paolo Sogono, Mathias Bressel, Steven David, Mark Shaw, Sarat Chander, Julie Chu, Nikki Plumridge, Keelan Byrne, Nicholas Hardcastle, Tomas Kron, Greg Wheeler, Gerard G Hanna, Michael MacManus, David Ball, Shankar Siva
International Journal of Radiation: Oncology - Biology - Physics | Published : 2021
PURPOSE: Fewer attendances for radiation therapy results in increased efficiency and less foot traffic within a radiation therapy department. We investigated outcomes after single-fraction (SF) stereotactic body radiation therapy (SBRT) in patients with oligometastatic disease. METHODS AND MATERIALS: Between February 2010 and June 2019, patients who received SF SBRT to 1 to 5 sites of oligometastatic disease were included in this retrospective study. The primary objective was to describe patterns of first failure after SBRT. Secondary objectives included overall survival (OS), progression-free survival (PFS), high-grade treatment-related toxicity (Common Terminology Criteria for Adverse Even..View full abstract