Time to pregnancy after a prepregnancy very-low-energy diet program in women with obesity substudy of a randomized controlled trial

Abstract

Objective: To examine the impact of a prepregnancy very-low-energy diet (VLED) program on time to pregnancy in women with obesity. Design: Substudy of a two-arm parallel group randomized controlled trial. Setting: Multiple tertiary care centers. Patient(s): Women 18–38 years old with obesity (body mass index 30–55 kg/m2 ) and planning conception. Intervention(s): One hundred sixty-four normoglycemic women with body mass index 30–55 kg/m2 , aged 18–38 years, and planning pregnancy were recruited through a social media platform for a two-arm randomized controlled trial. Women were allocated to a 12-week standard dietary intervention (SDI) or modified VLED. Completers of the intervention were o..