Journal article

Hemodynamic Response to Fluid Boluses for Hypotension in Children in a Cardiac ICU

Ben Gelbart, Anatole Harrois, Lauren Gardiner, Cherie Mcgregor, Laurent Bitker, Eva Van Zanten, Emma Beel, Rinaldo Bellomo, Trevor Duke, Warwick Butt

PEDIATRIC CRITICAL CARE MEDICINE | LIPPINCOTT WILLIAMS & WILKINS | Published : 2021

Abstract

OBJECTIVES: To describe the hemodynamic response to fluid boluses for hypotension in children in a cardiac ICU. DESIGN: A prospective, observational study. SETTING: Single-centered cardiac ICU. PATIENTS: Children in a cardiac ICU with hypotension. INTERVENTIONS: Clinician prescribed fluid bolus. MEASUREMENTS AND MAIN RESULTS: Sixty-four fluid boluses were administered to 52 children. Fluid composition was 4% albumin in 36/64 (56%), 0.9% saline in 18/64 (28%), and cardiopulmonary bypass pump blood in 10/64 (16%). The median volume and duration were 5.0 mL/kg (interquartile range, 4.8-5.4) and 8 minutes (interquartile range, 4-19), respectively. Hypovolemia/low filling pressures was the most c..

View full abstract