Journal article

Systematic review and consensus definitions for the Standardized Endpoints in Perioperative Medicine (StEP) intiative: cardiovascular outcomes

W Scott Beattie, Manoj Lalu, Matthew Bocock, Simon Feng, Duminda N Wijeysundera, Peter Nagele, Lee A Fleisher, Andrea Kurz, Bruce Biccard, Kate Leslie, Simon Howell, Giovani Landoni, Hilary Grocott, Andre Lamy, Toby Richards, Paul Myles

British Journal of Anaesthesia | ELSEVIER SCI LTD | Published : 2021


BACKGROUND: Adverse cardiovascular events are a leading cause of perioperative morbidity and mortality. The definitions of perioperative cardiovascular adverse events are heterogeneous. As part of the international Standardized Endpoints in Perioperative Medicine initiative, this study aimed to find consensus amongst clinical trialists on a set of standardised and valid cardiovascular outcomes for use in future perioperative clinical trials. METHODS: We identified currently used perioperative cardiovascular outcomes by a systematic review of the anaesthesia and perioperative medicine literature (PubMed/Ovid, Embase, and Cochrane Library). We performed a three-stage Delphi consensus-gaining p..

View full abstract