Journal article

Neurocognitive functioning during symptomatic states and remission in bipolar disorder and schizophrenia: A comparative study

Deniz Ceylan, Berna Binnur Akdede, Emre Bora, Ahmet Yigit Aktener, Ceren Hidiroglu Ongun, Zeliha Tunca, Koksal Alptekin, Aysegul Ozerdem

Psychiatry Research | ELSEVIER IRELAND LTD | Published : 2020


Aims Patients with bipolar disorder present milder cognitive impairment in comparison to patients with schizophrenia. Psychotic symptoms are associated with poorer cognitive functioning in both disorders. We aim to compare cognitive dysfunction between bipolar disorder and schizophrenia across symptomatic and remitted states. Methods An extensive cognitive battery was used to assess bipolar disorder patients (32 in manic episodes with psychotic features, 44 in euthymia), patients with schizophrenia (41 symptomatic, 39 remitted), and 55 healthy controls. A global cognitive factor and six neurocognitive domain factors were identified using principal component analyses. Results Global cognition..

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University of Melbourne Researchers