Investigating the lateralisation and disconnection model of social functioning in Agenesis of the Corpus Callosum using cognitive neuroscience techniques

Abstract

Recent research has begun to characterise the nature of social dysfunction in individuals with agenesis of the corpus callosum (ACC). Typical lateralisation of function coupled with disrupted interhemispheric transfer between the cerebral hemispheres has been proposed to account for the difficulties observed on various socio-emotional tasks in ACC, ranging from basic emotion perception through to higher-level nonliteral language comprehension and social reasoning. It has also been speculated that this laterality and disconnection model applies to social difficulties experienced in everyday life. The key underlying assumptions of the model have not been directly addressed, however. Specifical..