Journal article

Interferome v2.0: an updated database of annotated interferon-regulated genes.

Irina Rusinova, Sam Forster, Simon Yu, Anitha Kannan, Marion Masse, Helen Cumming, Ross Chapman, Paul J Hertzog

Nucleic Acids Research | Published : 2013

Abstract

Interferome v2.0 (http://interferome.its.monash.edu.au/interferome/) is an update of an earlier version of the Interferome DB published in the 2009 NAR database edition. Vastly improved computational infrastructure now enables more complex and faster queries, and supports more data sets from types I, II and III interferon (IFN)-treated cells, mice or humans. Quantitative, MIAME compliant data are collected, subjected to thorough, standardized, quantitative and statistical analyses and then significant changes in gene expression are uploaded. Comprehensive manual collection of metadata in v2.0 allows flexible, detailed search capacity including the parameters: range of -fold change, IFN type,..

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University of Melbourne Researchers