Journal article

Cardiovascular Health Profile at Age 25 Years in Adults Born Extremely Preterm or Extremely Low Birthweight

Jeanie LY Cheong, Anjali Haikerwal, John D Wark, Louis Irving, Suzanne M Garland, George C Patton, Michael M Cheung, Lex W Doyle

Hypertension | LIPPINCOTT WILLIAMS & WILKINS | Published : 2020


Being born extremely preterm (EP; <28 weeks' gestation) or extremely low birthweight (ELBW; <1000 g birthweight) may predict increased cardiometabolic risk in adulthood, but other early life predictors are less well described. We aimed to (1) compare cardiovascular health profiles between 165 adults born EP/ELBW and 127 controls at age 25 years, drawn from a prospective longitudinal cohort study, recruited at birth in 1991 to 1992; and (2) in the EP/ELBW group, determine early life associations of cardiovascular health. Cardiovascular health profiles were calculated individually for measures of anthropometry, abdominal visceral fat, blood pressure, fasting plasma glucose, insulin, lipids, C-..

View full abstract


Awarded by National Health and Medical Research Council of Australia

Funding Acknowledgements

Supported by grants from the National Health and Medical Research Council of Australia (Centre of Research Excellence No. 1060733; Project Grant No. 1104300; Career Development Fellowship No. 1141354 to J.L.Y. Cheong; and Senior research fellowship No. 1117873 to G.C. Patton), and the Victorian Government's Operational Infrastructure Support Program. The funding bodies had no role in the study design, the collection, analysis, or interpretation of data, or the writing of the article.