Thesis / Dissertation

Breast cancer associations with mammographic density defined by higher pixel brightness thresholds

Tuong Linh Nguyen, Mark Jenkins (ed.)

Published : 2016

Abstract

Mammographic density has conventionally been defined as the area of the mammographic image of the breast that is white or bright, and is presumed to reflect differing amounts of fibroglandular breast tissues and fatty tissue. The current gold standard measurement of this concept has been using the computer-assisted thresholding program called CUMULUS. I call these measures Cumulus. For women of the same age and body mass index (BMI), Cumulus measures of mammographic density have been well established to be a risk factor for breast cancer. Multiple case-control studies nested within cohorts of women attending mammographic screening services have found that Cumulus measures of mammographic de..

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