Comparative analysis of the faecal virome of dogs with various inflammatory intestinal diseases

Abstract

Little is known about the population of viruses present in the intestine of dogs, the virome, despite advances in molecular biology techniques. The viral flora in the intestine of dogs has been mostly studied in disease settings, targeted to known pathogenic viruses. There is currently a gap in our knowledge of the faecal canine virome present in healthy conditions. This study aimed to identify and characterise the virome present in faeces of healthy dogs compared to the virome present in dogs with acute diarrhoea and dogs with chronic enteropathy. Faecal samples were collected from 8 healthy dogs, 8 dogs with acute diarrhoea and 8 dogs with chronic enteropathy. A viral enrichment protocol, ..