Thesis / Dissertation

Viable But Non-Culturable (VBNC) state in Salmonella Typhimurium

Venkata Durga Naga Bhaskara Karthik Pullela, Richard Strugnell (ed.)

Published : 2019

Abstract

Salmonella enterica serovar Typhimurium is a dangerous food-borne pathogen that causes severe diseases like gastroenteritis and septicaemia. It causes over 800,000 deaths p.a. globally. The majority of the cases are caused by contaminated food. Culturing is still a gold standard to detect bacteria in food, clinical and other samples and this approach assumes that those bacteria present in the samples, which are capable of causing disease, are culturable. There are numerous reports of bacteria entering the viable but non-culturable (VBNC) state, a state where bacteria exhibit loss of culturability under routine culturing conditions despite being alive, when placed under stress conditions. The..

View full abstract