A study of Thromboprophylaxis in the Australian and New Zealand Fontan population

Abstract

Background: The Fontan procedure was developed approximately 50 years ago and has become the definitive treatment for children born with single ventricle physiology. Surgical refinement of the Fontan technique and improvements to critical care have led to a dramatic reduction in mortality, with the vast majority of patients expected to live well into adulthood. The reduction in mortality has led to a shift in research efforts in the Fontan population towards defining the long-term expectations and identifying modifiable factors that can reduce Fontan-associated morbidity. Thrombosis and stroke represent important post-Fontan complications. As such, thromboprophylaxis with warfarin or as..