Thesis / Dissertation

Localisation of the Epileptogenic Zone from Interictal State MEG Data of Focal Epilepsy Patients

Rui Li, David Grayden (ed.)

Published : 2020

Abstract

Over twenty million people in the world have drug refractory epilepsy. Their seizures cannot be adequately controlled by medication. Epilepsy surgery can remove or alter abnormal brain areas where seizures start, which is the only way to cure epilepsy and can be an effective treatment for drug refractory epilepsy patients. Accurate localisation of the epileptogenic zone (EZ) is crucially important to achieve seizure freedom after surgery. Magnetoencephalography (MEG) is a non-invasive brain functional imaging technique with superb temporal resolution. Clinically, neurophysiologists visually annotate interictal spikes in MEG recordings and apply localisation methods using averaged spikes. Th..

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University of Melbourne Researchers