Determinants of uterine receptivity

Abstract

‘Uterine receptivity’ refers to the status of the uterus when the endometrium is available to accept the embryo for implantation. Optimal endometrial receptivity leads to normal embryo implantation processes that serve as a foundation for a healthy pregnancy. Over the last three decades, there have been many advances in embryology that have resulted in significant improvements in embryo viability and overall in vitro fertilization (IVF) success rates. It is believed that implantation failure due to reduced endometrial receptivity is one of the major remaining impediments to higher IVF pregnancy rates. In a normal ovulatory cycle, the receptive endometrium develops following sequential expos..