Thesis / Dissertation

The Role of Candida in Oral Lichen Planus (OLP)

Lara Marie DeAngelis, Michael McCullough (ed.)

Published : 2019

Abstract

Purpose: Oral lichen planus (OLP) is a chronic condition characterised by T cell mediated destructions that is currently of unknown cause. OLP can be variably symptomatic with some patients experiencing no symptoms and others requiring extensive symptomatic management. Candida spp. can be found in association with OLP and due to this prophylactic treatment for Candida spp. is usually accounted for in the symptomatic management of OLP. This is despite current evidence not supporting concurrent use of antifungal therapy in the management of OLP with topical steroids. A potential hypothesis for the cause of OLP is an interaction of host genetic susceptibility combined with an environmental tri..

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