Thesis / Dissertation

Quantification of the dynamics of antibody response to malaria in pregnant women

Aluthwala Domingu Vithanage Tharkeshi Thanuja Dharmaratne, Julie Simpson (ed.)

Published : 2020

Abstract

Malaria remains a major public health threat with pregnant women and young children the most vulnerable populations. Approximately 125 million pregnant women are at risk of malaria infection every year. Immunity to malaria can significantly reduce the severity of malaria symptoms. This has long motivated efforts to better understand the immune response to malaria in order to develop an efficacious antimalarial vaccine. However, the complex behaviour of the immune system, particularly in pregnant women, has hindered identifying the underpinning mechanisms of the immune response to malaria infection. This project investigates antibody-mediated immunity in pregnant women who attended antenatal..

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