CuATSM PET to diagnose age-related diseases: a systematic literature review
Nada Majernikova, Jenny Jia Yu, Andrea B Maier
Clinical and Translational Imaging | SPRINGER-VERLAG ITALIA SRL | Published : 2020
Purpose: Cu(II)-diacetyl-bis(N4-methylthiosemicarbazone) positron emission tomography (CuATSM PET) is a non-invasive imaging technique that can be used to detect hypoxia and inform prognosis in cancer. Hypoxia and oxidative stress are also hallmarks of various age-related diseases. Whether CuATSM PET has a role in the evaluation of hypoxia and oxidative stress in age-related diseases has yet to be established. The aim of this systematic review is to evaluate the utility of CuATSM PET in the diagnosis and management of age-related diseases. Methods: EMBASE, Medline, Scopus, Web of Science and Psychinfo were systematically searched for articles published between January 1st 1997 and February 1..View full abstract
This study was supported by an unrestricted grant of the University of Melbourne, Australia received by Professor Andrea B. Maier.